Background: Dyspepsia is related to Helicobacter pylori and is among the most common reasons of military patients’ referring to Gastroenterology clinics. This study was performed to compare the efficacy of anti-Helicobacter pylori (anti-HP) and Proton Pump Inhibitors (PPI) treatment in patients with dyspepsia.
Materials and methods: This randomized clinical trial was performed on 160 patients with dyspepsia who were randomly received two treatment regimens including only PPI medicines and both PPI and anti-HP agents
Results: After the treatment, almost all symptoms had significantly less severity in the patients receiving anti-HP treatment compared with those receiving only PPI treatment (p<0.05).
Conclusion: According to the results, it is recommended that anti-HP treatment be used to improve the symptoms severity in patients with dyspepsia.