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:: Volume 19, Number 3 (Autumn 2017) ::
2017, 19(3): 32-40 Back to browse issues page
Effect of endurance training on serum Apelin levels, C-reactive protein and insulin resistance index in middle-aged sedentary men
R soori , M darabi, K ranjbar, A ramezankhani
Associate professor Department of Exercise Physiology, University of Tehran, Tehran, Iran , ramezankhanizm@gmail.com
Abstract:   (26 Views)

Background: Apelin is a novel adipokine that is closely related with insulin resistance. The aim of this study was to assess the effects of endurance training on Apelin, C-reactive protein (CRP) and insulin resistance index in middle-aged sedentary men.
Materials and methods: In this quasi-experimental study, 30 men aged between 48 to 60 years with body mass index (BMI) of ≥30 kg/m2, were randomly allocated to the endurance training (n=15), and control groups (n=15). The training program consisted of 12 weeks of endurance training (treadmill running) with 50-75% maximum heart rate. Before and 48 hours after the 12 weeks exercise, measurement of Apelin, CRP and insulin resistance index were performed. Paired t-test and Independent t-test were used for statistical analysis using SPSS software.
Results: Results revealed that after 12 weeks endurance training, significant reductions were observed in the levels of CRP (p=0.001), BMI (p=0.001), fat percent (p=0.001), Apelin levels (p=0.027) and insulin resistance index (p=0.002) of experimental group compared to control group.
Conclusion: Generally, it seems that significant reductions in Apelin and CRP levels as a result of reduced body fat mass following 12 weeks of endurance training have been effective in reducing insulin resistance.

 

Keywords: Physical Endurance, Apelin, IL6, C Reactive Protein, Obesity, Sedentary Lifestyle
Full-Text [PDF 633 kb]   (9 Downloads)    
Type of Study: Research | Subject: General
Received: 2017/01/11 | Accepted: 2017/10/11 | Published: 2017/10/11
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soori R, darabi M, ranjbar K, ramezankhani A. Effect of endurance training on serum Apelin levels, C-reactive protein and insulin resistance index in middle-aged sedentary men. EBNESINA- Journal of Medical. 2017; 19 (3) :32-40
URL: http://ebnesina.ajaums.ac.ir/article-1-486-en.html
Volume 19, Number 3 (Autumn 2017) Back to browse issues page
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