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Rubella seroimmunity 6 years after the public vaccination against rubella-measles among students of conservatory Be'sat Hospital of IRI Air Force
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M Darvishi   , H Molana , M Afzali |
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Abstract: (16858 Views) |
Background: Rubella is a viral and acute disease which can be
observed in children and adults by symptoms such as lymphoid
glands inflammation and dermatitis. Its public health importance is
related to teratogenic effects of primary rubella in the first trimester
of pregnancy. Infection in this period of pregnancy causes various
anomalies such as cataract, glaucoma, deafness, coronaryvascular
disease, pneumonia, encephalitis, bone damage, blood
disorders, interference with the function of endocrine glands and
low weight birth.
Materials and methods: In this cross-sectional study the seroprevalence of
anti-rubella IgG antibodies investigated in 100 students of
conservatory Be'sat army hospital by ELISA. The cut-off values of
more than 11 IU/ml was considered positive for rubella antibodies.
The population divided into two groups: smoker and non smoker
which indicated smoking status in their families. BMI groups: <20,
20-25, 25-30, >30. Statistical analyses were performed by using
SPSS ver.16 software and chi-square test and p<0.05 was
considered significant.
Results: In 6% sera tested IgG antibody to rubella was under the
11 IU/ml and this population was not immune against rubella. In
94% sera tested IgG antibody more than11 IU/ml and was positive
for anti-rubella. There were no statistically significant relation
between smoking and antibody levels and also between different
BMI groups and antibody levels.
Conclusion: The results showed that the immunity to rubella virus has
increased. Therefore, with presence of high immunity of pregnant
women to rubella virus, public vaccination against rubella is not
recommended. |
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| Keywords: Pregnancy, Rubella, Immunity, Vaccination, Congenital Rubella, Antibody titer |
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Full-Text [PDF 309 kb]
(3292 Downloads)
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Type of Study: Original |
Received: 2012/03/7 | Accepted: 2014/06/3 | Published: 2014/06/3
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