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:: Volume 11, Issue 2 (Winter 2009) ::
EBNESINA 2009, 11(2): 33-39 Back to browse issues page
Meningococcal infection and its effective antibiotics
K Abedini , M Darvishi, S Zareiy, M Samadpoor, A Eskandari
Abstract:   (13507 Views)
N. meningitidis is a gram-negative diplococcus that is a strict human pathogen. It most commonly causes asymptomatic nasopharyngeal carriage but on occasion causes invasive disease. Discussions of meningococcal epidemiology and prevention necessarily include meningococcal serogroups. Pathogenic strains of N. meningitidis have a polysaccharide capsule, which serves as a major virulence factor for this organism. Unencapsulated strains, frequently found in the nasopharynx of asymptomatic carriers, rarely cause invasive disease. There are specific host factors that increase the risk of invasive meningococcal infection because only a minute fraction of nasopharyngeal carriers of N. meningitidis develop clinical disease. Therapy requires the prompt administration of antibiotics following the collection of appropriate diagnostic specimens. The therapy of choice is penicillin or ampicillin because the meningococcus remains susceptible to these agents around the world. The prevalence of carriage varies by study but is generally highest in adolescents and young adults.
Keywords: N. meningitides, Antibiotics, Meningococcal infection
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Type of Study: Original |
Received: 2012/03/7 | Accepted: 2014/06/3 | Published: 2014/06/3
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Abedini K, Darvishi M, Zareiy S, Samadpoor M, Eskandari A. Meningococcal infection and its effective antibiotics. EBNESINA. 2009; 11 (2) :33-39
URL: http://ebnesina.ajaums.ac.ir/article-1-63-en.html

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Volume 11, Issue 2 (Winter 2009) Back to browse issues page
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