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Comparison of zinc plasma level in people with and without HIV infection in Imam Khomeini Hospital, 2006
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AR Soudbakhsh   , H Khalili , M Rasoulinezhad , M Haj-Abdolbaghi , AA Saidi , M Aminiyanfar |
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Abstract: (11587 Views) |
Background: Zinc is one of the essential micronutrients and its role in
immune system function is an interesting matter for researchers.
HIV/AIDS as an immune system disorder, presents with impairing in
elements of immune system. This study was designed for
assessment of zinc level of serum in a group of HIV+ patients and
compare with non-HIV people. Determining relationship between
zinc level of serum and count of immune cells was another aim of
this study.
Materials and methods: This cross-sectional study was conducted with 96
people in 2 groups: 48 HIV+ and 48 HIV-. HIV negative group was
divided in 2 subgroups: IV Drug Users (IDUs) and non-IDUs. Zinc
level of serum was measured with atomic absorption method and
statistical analysis was conducted with SPSS software. Levels of
zinc were compared in different groups.
Results: Overall means of zinc plasma level of main groups had
significant differences, and HIV+ group showed a significant
difference with two other groups. In addition, two groups of HIV- had
significant difference. There was a relationship between count of
CD4 cells and zinc level of serum. Zinc showed lowest level in HIV+
IDUs, then HIV- IDUs and finally HIV- non-IDUs.
Conclusion: Results demonstrate zinc level impairment in HIV+ cases
and its association with decrease in determinant parameters of
survival such as count of CD4 cells. |
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| Keywords: micronutrient, zinc, HIV, AIDS |
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Full-Text [PDF 324 kb]
(1745 Downloads)
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Type of Study: Original |
Received: 2012/03/7 | Accepted: 2014/06/3 | Published: 2014/06/3
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