Background: Researching laboratories as using wide range of chemical substances assign part of chemical accidents occurring horrible accidents in laboratories of our country in recent years, show requirement to create systematic approach to health and safety hazards risk management.
Materials and methods: This research is a resolution-descriptive Study and doing for 14 researches and experiments in clinics and educational-research laboratories in Shahid Beheshti University of Medical Science. Before any assessment for variety of activities in a research center, information gathered with observation and interview, about work practice and type of chemical substances. As in experiment or research process in many cases, chemical substances use in unlike mother concentration, after calculating all chemical substances mother concentration and according to first risk phrase and physical and chemical properties of substances and second risk phrases calculated with using approved criteria for classifying hazardous substances by national occupational health and safety commission (Australian government). For quantification of risk result we use 3*3 probability – severity matrix with attention to consequence of exposure and Out come of this exposure with qualitative and quantitative assessment of control measures.
Results: This study shows 93% of exposures have moderate risk and 7% of exposures have low risks. Highest hazardous exposure related to school of public health, nerve research center and school of medicine and lowest risk was for department of immunology.
Conclusion: This research show assessment of Occupational exposure risk to harmful chemical agents, can representation worth information about preventive and control measures.