Abstract Background: In recent years, infrared thermography tools are used for viral disease detection. However, no study has been to evaluate the value of this device. The current study was designed to review the effectiveness of infrared thermography technique for diagnosis of viral diseases in international airports. Materials and methods: This study was conducted as a systematic review. All of the relevant databases, bibliography of related papers, and companies’ websites were searched using appropriate search strategies and keywords. Results: Totally, 121 papers were recovered in total using different databases and search techniques. Considering the research selection criteria, 13 papers were recognized as suitable. Conclusion: The results showed that although infrared thermography is a safe, rapid and cheap technique in screening and diagnosis of different diseases, current studies do not show any acceptable diagnostic value compared to other diagnostic techniques. It is recommended to use the infrared thermography as a complementary technique