Background: In recent years with the increasing popularity of non­invasive and low-invasive methods, the smart clothing application - either as professional recognizing tools for medical analysis or in domestic usage- has increased. Such systems could be in service of tele­medicine and aero-military medicine as well.
Materials and methods: In this article, after systematic review on previous researches, the paper made a report on author’s research project in AJA University of Medical Science about smart clothing design for pilots. The report aimed to point out the process, models, conceptual design, specifications and capabilities of this multi-parametric sensing system, alongside with the future challenges of applying these healthcare systems.
Results: Information received from this system could be stored as pilot's health database and used for long-term monitoring, screening and operational interpretations. Another application is online monitoring of vital signs that could be integrated with neurofeedback operations in military context.
Conclusion: Success of these products not only relies on applying user­centered methods but also depends on technical test loops and usability analysis. Moreover, it’s essential to overcome on some issues of ethics, reliability, inter-operability, user acceptance of technology and technical development challenges for widespread and efficient applications in future.