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Studying the relationship between previous Chlamydia pneumonia infection with atherosclerotic coronary artery disease
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M Darvishi *   , N Fazeli , M Kooshk zari , S Zareiy |
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Abstract: (14569 Views) |
Background: Ischemic heart disease is the most common cause of
mortality and morbidity in developed countries. In recent years,
atherosclerosis has been introduced as an inflammatory and
immunological disease in response to vascular injury. In addition, it
is proposed to be associated with the infectious diseases such as
Chlamydia pneumonia. The aim of this study is to evaluate anti-
Chlamydia antibody in CAD patients and normal population.
Materials and methods: In a case - control study, 80 subjects were divided
into two groups based on their angiography .The data contains
demographic and medical information such as age, gender, history
of diabetes, hypertension, smoking status and etc. Blood samples
were sent to laboratory for biochemical and immunological
assessments. Antibody titers of 5urb/ml and higher was considered
as positive.
Results: Anti-Chlamydia pneumonia antibody was positive in 76.2% of
study population. 90% of cases and 62.5% of the control group had
positive antibody which is statistically significant.
Conclusion: The results indicate a positive relationship between
previous Chlamydia pneumonia infection and CAD. And also it is
showed that previous infection with this microorganism should be
considered as a risk factor for CAD. |
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| Keywords: Chlamydia pneumonia, Antibody IgG, Coronary artery disease |
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Full-Text [PDF 266 kb]
(1989 Downloads)
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Type of Study: Original |
Received: 2012/03/6 | Accepted: 2014/06/3 | Published: 2014/06/3
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