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:: Volume 12, Issue 4 (Winter 2010) ::
EBNESINA 2010, 12(4): 4-8 Back to browse issues page
Studying the relationship between previous Chlamydia pneumonia infection with atherosclerotic coronary artery disease
M Darvishi , N Fazeli, M Kooshk zari, S Zareiy
Abstract:   (12430 Views)
Background: Ischemic heart disease is the most common cause of mortality and morbidity in developed countries. In recent years, atherosclerosis has been introduced as an inflammatory and immunological disease in response to vascular injury. In addition, it is proposed to be associated with the infectious diseases such as Chlamydia pneumonia. The aim of this study is to evaluate anti- Chlamydia antibody in CAD patients and normal population.
Materials and methods: In a case - control study, 80 subjects were divided into two groups based on their angiography .The data contains demographic and medical information such as age, gender, history of diabetes, hypertension, smoking status and etc. Blood samples were sent to laboratory for biochemical and immunological assessments. Antibody titers of 5urb/ml and higher was considered as positive.
Results: Anti-Chlamydia pneumonia antibody was positive in 76.2% of study population. 90% of cases and 62.5% of the control group had positive antibody which is statistically significant.
Conclusion: The results indicate a positive relationship between previous Chlamydia pneumonia infection and CAD. And also it is showed that previous infection with this microorganism should be considered as a risk factor for CAD.
Keywords: Chlamydia pneumonia, Antibody IgG, Coronary artery disease
Full-Text [PDF 266 kb]   (1352 Downloads)    
Type of Study: Research | Subject: General
Received: 2012/03/6 | Accepted: 2014/06/3 | Published: 2014/06/3
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Darvishi M, Fazeli N, Kooshk zari M, Zareiy S. Studying the relationship between previous Chlamydia pneumonia infection with atherosclerotic coronary artery disease. EBNESINA. 2010; 12 (4) :4-8
URL: http://ebnesina.ajaums.ac.ir/article-1-43-en.html


Volume 12, Issue 4 (Winter 2010) Back to browse issues page
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