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:: Volume 10, Issue 3 And 4 (Autumn & Winter 2007) ::
EBNESINA 2007, 10(3 And 4): 15-22 Back to browse issues page
Comparison of zinc plasma level in people with and without HIV infection in Imam Khomeini Hospital, 2006
AR Soudbakhsh, H Khalili, M Rasoulinezhad, M Haj-Abdolbaghi, AA Saidi , M Aminiyanfar
Abstract:   (10355 Views)
Background: Zinc is one of the essential micronutrients and its role in immune system function is an interesting matter for researchers. HIV/AIDS as an immune system disorder, presents with impairing in elements of immune system. This study was designed for assessment of zinc level of serum in a group of HIV+ patients and compare with non-HIV people. Determining relationship between zinc level of serum and count of immune cells was another aim of this study.
Materials and methods: This cross-sectional study was conducted with 96 people in 2 groups: 48 HIV+ and 48 HIV-. HIV negative group was divided in 2 subgroups: IV Drug Users (IDUs) and non-IDUs. Zinc level of serum was measured with atomic absorption method and statistical analysis was conducted with SPSS software. Levels of zinc were compared in different groups.
Results: Overall means of zinc plasma level of main groups had significant differences, and HIV+ group showed a significant difference with two other groups. In addition, two groups of HIV- had significant difference. There was a relationship between count of CD4 cells and zinc level of serum. Zinc showed lowest level in HIV+ IDUs, then HIV- IDUs and finally HIV- non-IDUs.
Conclusion: Results demonstrate zinc level impairment in HIV+ cases and its association with decrease in determinant parameters of survival such as count of CD4 cells.
Keywords: micronutrient, zinc, HIV, AIDS
Full-Text [PDF 324 kb]   (1322 Downloads)    
Type of Study: Research | Subject: General
Received: 2012/03/7 | Accepted: 2014/06/3 | Published: 2014/06/3
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Soudbakhsh A, Khalili H, Rasoulinezhad M, Haj-Abdolbaghi M, Saidi A, Aminiyanfar M. Comparison of zinc plasma level in people with and without HIV infection in Imam Khomeini Hospital, 2006. EBNESINA. 2007; 10 (3 and 4) :15-22
URL: http://ebnesina.ajaums.ac.ir/article-1-73-en.html


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